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Total Disc Replacement an Effective Alternative to One-Level ACDF

Five-year study results support safety, effectiveness of replacing cervical disc.

Compared with anterior cervical disc fusion at one-level, total disc replacement may be an effective treatment for symptomatic degenerative disc disease, study data indicates.

According to Michael S. Hisey, M.D., similar improvements in neck disability index scores, visual analog scale neck and arm pain scores, and SF-12 scores were evident in patients who received either one-level total disc replacement (TDR) or anterior cervical disc fusion (ACDF) at 60 months postoperatively.

“Five-year results support the safety and effectiveness of the Mobi-C disc as a noninferior alternative to ACDF for one-level treatment,” said Hisey, an orthopedic surgeon at the Texas Back Institute in Denton and Flower Mound, Texas.

A total of 164 patients received TDR with the Mobi-C Cervical Disc Prosthesis and 81 patients underwent ACDF with anterior plate and allograft bone. The follow-up period began at six weeks postoperatively and ended at 60 months postoperatively.

Three percent of patients who underwent TDR had reoperations, compared with 11.1 percent of patients who underwent ACDF, according to Hisey. Additionally, patients who underwent TDR maintained their range of motion throughout the 60-month follow-up.

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